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Subsequent to the approval of exenatide, additional GLP-1 RAs have been FDA-approved, with differences across agents in indication for use (eg, pediatrics), route and/or intervals of administration, pharmacology, efficacy, and tolerability

doi: 10.1056/NEJMoa1504720

These medications work by mimicking the action of the naturally occurring GLP-1 hormone, which is released from the intestine in response to food intake
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