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People with type 2 diabetes or pancreas problems also have an increased risk of getting ketoacidosis

In the emergency setting, clinicians will perform blood tests to measure pancreatic enzymes (lipase and amylase) and assess for complications

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Pyruvate carboxylase is a critical enzyme in gluconeogenesis (the formation of glucose from sources other than carbohydrates, such as pyruvate, lactate, glycerol, and the glucogenic amino acids)

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Conclusion Enavogliflozin added to metformin significantly improved glycemic control in patients with T2DM and was non-inferior to dapagliflozin 10 mg, suggesting enavogliflozin as a viable treatment option for patients with inadequate glycemic control on metformin alone