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Key Takeaways Retatrutide (LY3437943) is an investigational weight loss medication developed by Eli Lilly Triple-agonist mechanism: First drug to activate GLP-1, GIP, and glucagon receptors simultaneously Phase 2 results: Up to 24.2% weight loss at 48 weeks (approximately 58 lbs for a 240-lb person) Not FDA-approved: Currently in Phase 3 clinical trials, expected approval in 20272028 How it differs: Outperforms semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound) in weight loss trials Access now: Clinical trials (free), compounding pharmacies, or research peptide vendors What Is Retatrutide

Last updated: August 2023

Make sure to give your healthcare provider a comprehensive list of all the medicines, herbal products, non-prescription drugs (over-the-counter medicines), and dietary supplements you are currently using while on semaglutide

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However, if cost, customization, or personalized genetic insights matter to you, compounded semaglutide from PlexusDx offers superior value and flexibility