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These data are in agreement with non-controlled clinical studies reporting that 72 h of native GLP-1 infusion improved regional and global left ventricular performance in patients with acute myocardial infarction and severe systolic dysfunction [619]

Available online at: (Accessed 9 July 2024)

Moreover, insulin affects the hypothalamic-pituitary system

It may also interact with medications metabolised by cytochrome P450 enzymes, affecting drug levels of various medications including statins and anticoagulants

doi: 10.3390/ijms2217945

When estrogen swings, your sleep becomes lighter, your recovery slows down, and your nervous system works harder to keep you regulated