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Some individuals find that alternating between two dose levels provides effective maintenance at lower average doses than continuous higher dosing

The body mass index (BMI) of individuals with IBD has seen an upward shift with 15%-40% of adult patients reported to be obese and 20%-40% overweight

Further, the accumulation of AGEs in the extracellular matrix increases the activity of metalloproteinases and therefore reduces collagen and elastin synthesis [25]

Di Meo S, Iossa S, Venditti P

Originally used to manage type 2 diabetes, semaglutide is now FDA-approved for chronic weight management in qualifying individuals

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