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Retatrutide vs Semaglutide: Evidence-based comparison of the investigational triple GIP/GLP-1/glucagon agonist versus the FDA-approved GLP-1 agonist

DRUG OF THE DAY Tirzepatide Class: Dual GIP and GLP-1 Receptor Agonist MOA: Activates GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors enhances insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite improves blood sugar control and promotes weight loss

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Age-Related Conditions 1. Sarcopenia: The ability of MOTS-c to preserve muscle function could help address age-related muscle loss[5][2]
