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Considering this biphasic weight pattern in PD, the dual action of GLP-1 RAs, reducing insulin resistance while inducing weight loss, raises important considerations regarding their long-term metabolic effects in PD patients with varying phenotypes and nutritional profiles

- Akkermansia muciniphila: Generates postbiotics that induce GLP-1 production

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Cardiovascular risk reduction For type 2 diabetes patients with established cardiovascular disease, GLP-1 receptor agonists are preferred over insulin due to their proven cardiovascular benefits

Are Glucagon-like peptide-1 (GLP-1) receptor agonists Central Nervous System (CNS) penetrant: a narrative review

[15] [16] A diet rich in fruits, vegetables, whole grains, and legumes can support both healthy weight loss and digestive health