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Corroborating these findings, other GLP-1RAs have similarly shown neuroprotective properties in murine models of ocular hypertensive glaucoma, manifesting as enhanced RGC survival, reduced microglial/macrophage activation, and amelioration of optic nerve axon degeneration [46]

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Use a 0.3 ml (30-unit) syringe for doses under 25 units whenever possible

Real-world data suggests 15-25% of patients maintain 75% or more of their weight loss for two years without continued treatmentthese individuals typically combine rigorous diet adherence, regular strength training, and sustained behavioral modifications

Upon infusion, GLP-1 exerts potent vasodilatory effects on conduit artery and arterioles in healthy humans leading to increased blood flow for enhanced microvascular recruitment and muscular perfusion 46

Second, an initial prescription was used as intent to treat however, we did not require people to have a subsequent medication dispense