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Using a diet-induced obesity (DIO) mouse model, we examined the effects of PT150 alone and in combination with semaglutide on body weight, food intake, glucose tolerance, and pancreatic immune cell infiltration during active treatment and following drug washout

The impact of food bioactives on health: in vitro and ex vivo models

Current evidence suggests that benefitsboth glycemic control and weight reductionare maintained with continued treatment, but discontinuation frequently results in weight regain and worsening of metabolic parameters

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Labs were notable for a mild elevation in liver enzymes, elevated troponin, high NT-proBNP and elevated lactate

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