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2020, doi: 10.1038/s41574-020-0399-8

Hainer V, Toplak H, Mitrakou A

GLP-1 RAs were created after endogenous glucagon-like peptide-1 (GLP-1) was discovered in the 1980s by Jens Juul Host and Joel Habener [1,2]

The kidneys of liraglutide-treated mice also showed reduced DNA binding ability of NF-B, decreased MCP-1 levels, and increased IL-10 levels
GLP-1RAs have multifaceted biological functional properties, positioning them as a potential therapeutic option for DPN
