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18 Exendin-4, a GLP-1 analogue, also elicits protection against neuroinflammation, which is linked to a decrease in stroke risk

Lancet 397(10278):971984 [DOI] [PubMed] [Google Scholar] 20.Shi I, Khan SS, Yeh RW, Ho JE, Dahabreh IJ, Kazi DS (2025) Semaglutide Eligibility Across All Current Indications for US Adults

Their primary concern is blood sugar destabilization

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at 8 weeks and every 8 weeks thereafter, participants were assessed based on A1C response to determine if a dose adjustment was warranted

But notably those with obesity had a slightly lower prevalence rate ratio, so maybe less alcohol use as compared to those without obesity. There are some limitations of the analysis, she acknowledged, pointing to the cross-sectional design and the possibility of unmeasured confounding