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SGLT2 inhibitors improve glycemic control by blocking SGLT2 receptor-mediated reabsorption of glucose in the proximal convoluted tubule, where 80-90% of this reuptake occurs, and increased downstream excretion of glucose and sodium chloride

Authors : Yan-fang Chang, Di Zhang, Wei-min Hu, Dong-xing Liu, Lin Li Source : This in vitro study investigated the neuroprotective effects of semaglutide in a SH-SY5Y cell line model of Alzheimers disease, induced by amyloid- 25-35 (A25-35)

Retatrutide is still in Phase 3 clinical trials and has not yet received FDA approval

Although GLP-1 clearly had therapeutic potential, s.c