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"Once-Weekly Semaglutide in Adults with Overweight or Obesity." New England Journal of Medicine 384(11): 989 5
GLP-1RAs should not be considered first-line therapy for overt HF, as they represent a valuable tool in the prevention and early modulation of HFpEF in patients with metabolic risk
Additionally, this trial also reported that compared with placebo, sotagliflozin was more frequently associated with diarrhea, genital candidiasis, hypovolemia and diabetic ketoacidosis
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