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In addition, the GLP-1 can inhibit postprandial gastric emptying and reduce gastric acid secretion, inhibit gastric and duodenal peristalsis by inhibiting vagus nerve, and increase the pressure of pylorus, thus reducing appetite, causing a reduction in body weight and participating in the so-called ileal braking effect (35)

GLP are NOT associated with clinically significant bone loss

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Hepatology 2012

Taking semaglutide was associated with approximately a 11% higher absolute risk of preterm birth

Suresh Ramalingam, executive director of Winship Cancer Institute of Emory University and the trials principal investigator, called the approval a major breakthrough for this patient group