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Biologic GLP-1 receptor agonists are produced using recombinant technology

J Diabetes Investig 6(2):164172

11 However, a dose-specific analysis revealed that the beneficial effect of efpeglenatide on HF hospitalisation was primarily seen in the 6 mg group, in which there was a 50% RRR in HF hospitalisation (HR 0.50)

Recently, it was demonstrated that exendin-4, which is a GLP-1 receptor agonist, also known as exenatide, currently prescribed to treat obesity and diabetes, reduces Na+/K+ATPase activity a marker of CSF secretion

Diabetes Endocrinol

Their dual effects on weight and alcohol consumption highlight the shared biology underlying metabolic and addictive disorders