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Additionally, in pre-clinical mouse models, DA-1726 elicited similar weight reduction, while consuming more food, compared to tirzepatide and survodutide, while also preserving lean body mass and demonstrating lipid-lowering effects compared to survodutide

Benning TJ, Heien HC, Herges JR, Creo AL, Al Nofal A, McCoy RG

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"Patients are in a precarious situation right now," Noorian said

Rapid or excessive weight loss can increase the risk of gallstones, loss of muscle mass and bone density, and nutritional deficiencies. Some people, including older adults, postmenopausal women, and individuals whose weight loss approaches a range considered underweight may be at particularly increased risk for negative health impacts from rapid or excessive weight loss, Moiz says