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Description
The most potent molecules5, 6, and 7 (Figure 3)also had their oral antihyperglycemic efficacy assessed

Ex-4 is unclear

The United States accounts for approximately 40% of global GLP-1 use, though adoption is accelerating in Europe, Australia, and other developed markets as awareness and reimbursement expand

doi: 10.2337/dc16-0046 58 GarveyWTBirkenfeldALDickerDMingroneGPedersenSDSatylganovaAet al

C.BrubakerP
This includes studying their absorption, distribution, metabolism, and excretion in the body, which dictates their bioavailability and efficacy