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Description
This personalized approach is a core part of the modern treatment of obesity
The reason this topic receives so much attention is the semaglutide cardiovascular outcomes trial SUSTAIN-6, in which diabetic retinopathy complications were reported more often in the semaglutide group than in the placebo group
The Triple Agonists The so-called triple agonists like retatrutide hit a new hierarchy of hormone receptors: GLP-1, GIP, and glucagon to reduce appetite, control blood sugar, and increase energy expenditure

The first is between the three "pure" GLP-1 medications
Roughly 14% (1 out of every 7 women) on commercial clomiphene therapy experience uncomplicated ovarian enlargement

Obesity : preventing and managing the global epidemic : report of a WHO Consultation on Obesity, Geneva, 3-5 June 1997
