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70 GLP-1RAs confer substantial benefits for individuals with AS owing to their multifaceted impact on various aspects of cardiovascular health

Some evidence suggests that exercising in a fasted state promotes greater fat oxidation

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In a mouse model of AD, combining insulin with Ex-4 leads to the significant downregulation of the expression of insulin receptor signaling pathway genes in AD mice, which is associated with improved spatial learning

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By increasing the sensitivity of cells to insulin, GLP-1RAs help the body to regulate blood sugar levels more effectively, which can reduce the risk of developing NAFLD [21,22] (Figure 2)