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That is a meaningful positive signal
However, in the hypoglycaemic GB patients, GLP-1 appeared to account for about 45% of increased insulin secretion, not much more than in the non-hypoglycemic surgical subjects
GLP-1 receptors, found in the gut, pancreas and brain, play key roles in glucose regulation and appetite suppression
Nat Commun 13:4477
Mol Metab 44:101132
The 2023-2024 semaglutide shortage pushed many patients to tirzepatide
