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31 Thus GLP-1RA may, via GLP-1 receptor signaling in the hypothalamus, interfere with mRNA transcription, translation or the cleavage of ObRb to soluble leptin receptors and thereby down-regulate the production of soluble leptin receptors

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Barrea et al., 2019)

Healthy sleep patterns Poor sleep affects appetite hormones, making it harder to lose weight

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Serve about half of what you typically would to better manage portion sizes and minimize the risk of gastrointestinal discomfort