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Description
With the increasing obesity and AMD incidence in older adults, clarification of whether GLP-1 receptor agonists affect AMD risk independently of diabetes is clinically important

Metabolism and Chemical Degradation of New Antidiabetic Drugs: A Review of Analytical Approaches for Analysis of Glutides and Gliflozins

doi: 10.1210/endrev/bnaa032 [DOI] [PMC free article] [PubMed] [Google Scholar] 63.Christensen M, Vedtofte L, Holst JJ, et al
Results of the first phase 3 trial comparing orforglipron with oral semaglutide found that patients with diabetes lost on average 6-8% of their body weight with orforglipron, compared with 4-5% on semaglutide

If side effects are running harsh, for instance, a provider may keep you at your current dose instead of moving up
The patients met the following criteria for obesity surgery: body mass index of at least 40 or 35 kg/m 2 with at least two comorbidities (hypertension, type 2 diabetes, dyslipidemia, or obstructive sleep apnea syndrome)
