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Medical guidance and individual health factors should inform any decisions about alcohol use during GLP-1 therapy

It is one of the most extensively studied metabolic peptides in clinical research, with approved pharmaceutical formulations (Ozempic, Wegovy) demonstrating its significance in the incretin pathway

Patient-derived human islets from male and female cadaveric donors were 3D-cultured in solubilised extracellular matrix gel in co-culture with the same donor PBMCs, and incubated with cytokines (IL-1, TNF-, IFN-) for 2448 h in the presence of vehicle or increasing concentrations of the CB1R blocker JD-5037
