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The use and supplementation of LC have experienced a notable surge in developed nations

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OCTN2 contains a glucose-transporter signature motif between transmembrane domains 2 and 3 in which substitution of arginine 169 with glutamine, proline or tryptophan (all identified in patients with primary carnitine deficiency) impairs transporter function without impairing maturation to the plasma membrane [95]

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Primary end points also included hospitalization and oxygen requirements, with severity parameters defined by CDC pneumonia criteria (18)

[DOI] [PubMed] [Google Scholar] 55.Ozawa T, Fujiwara M, Harada T, Muraoka M, Ishii M