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purification and sequencing of porcine and bovine GIP revealed only minor differences (two amino acids in porcine and one in bovine) compared to the human GIP peptide (1618) [ Figure 2 ]

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The ESSENCE trial will provide valuable data on the maintenance of histological benefits over 240 weeks of continuous treatment, but long-term extension studies and off-treatment follow-up protocols are needed to characterize rebound kinetics

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