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Endocrinology 1986, 119, 14671475

doi:10.1016/S0006-8993(97)00648-3 135

No, GLP-1 and dual-agonist peptides are contraindicated during pregnancy and breastfeeding

This article briefly outlines the efficacy and safety data of the drug treatment pipeline for obesity, with a focus on incretin-based medications, and discusses the clinical challenges and significance brought about by this new era

Aim for 1.0-1.5 grams of protein per kilogram of ideal body weight daily, distributed across meals

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have been shown to reduce glycated hemoglobin levels via regulation of incretin function without secondary effects such as weight gain and hypoglycemia [4, 5]