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doi: 10.1007/s13300-020-00786-1

Quick Answer: Current evidence suggests a possible association between semaglutide and pancreatitis rather than a confirmed causal relationship, with clinical trials showing relatively low incidence rates

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How it causes swelling is thought to be due an osmotic shift

GLP-1 Native GLP-1 reduces adipogenesis via ERK-inhibition, downregulating PPAR , LPL , C/EBP and FABP4 [12, 22, 23, 31]

This article was previously distributed in the August 22, 2023, educational email of the Patient Safety Authority, available at About the Author Patient Safety Authority (patientsafety.pa.gov) is an independent state agency that oversees the Pennsylvania Patient Safety Reporting System (PA-PSRS), the largest database of its kind in the United States.