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These results highlight how difficult it is for adolescents to keep weight off once they lose it. Those taking exenatide had an increase of 8 bpm in heart rate from randomization to 1 year compared with a 1 bpm increase for placebo ( P = .03)

Source: Centers for Disease Control and Prevention (CDC)

The high cost is attributed to advanced research and development and drug shortages owing to huge demand

In rodents, non-shivering thermogenesis is mediated by the uncoupling protein-1 (UCP-1) in brown adipose tissue (51)
Table of Contents: Who is a good candidate for tirzepatide therapy for weight loss and what criteria determine eligibility

doi: 10.1016/j.biopsych.2019.10.012
