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Description
LY3298176 activated both GIP and GLP-1 receptor signaling in vitro and showed glucose-dependent insulin secretion and improved glucose tolerance by acting on both GIP and GLP-1 receptors in mice

Tirzepatide: A Dual Glucose-dependent Insulinotropic Polypeptide and Glucagon-Like Peptide-1 Agonist for the Management of Type 2 Diabetes Mellitus

Athletes subject to anti-doping testing should check current prohibited substance lists before using tirzepatide or any similar medication

Ambulatory blood pressure has been reduced with tirzepatide, which was partially, but not completely, related to weight changes [31], as have serum lipids, with reductions in LDL and non-HDL cholesterol after 72 weeks of tirzepatide [11]
Endocrine Society
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