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325 GIPR is downregulated in adipose tissue during insulin-resistant states, such as obesity, and several studies suggest that GIP augments insulin actions in adipose tissue
doi: 10.1111/febs.16151
R., Khushman M
It found its way into Jimmy Kimmel's opening monologue at the Oscars, and Chelsea Handler discussed how her doctor gave her Ozempic to lose some extra pounds (which isn't its purpose), though she didn't know she was on it
10.1016/j.bbr.2012.03.020 269
And it flourished in the 1970s until it all came crashing down in the AIDS epidemic
