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This guidance follows the FDAs approval of Wegovy (semaglutide) for an expanded indication to reduce the risk of major cardiovascular events (MACE), including cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in adults with established cardiovascular disease (CVD) and who are either obese or overweight

This side effect is similar across administration routes, with no major differences reported between oral and injectable forms

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Usually because your dose or your concentration changed and the old barrel no longer fits it well