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[15] Clinicians should conduct a comprehensive cardiovascular risk assessment before initiating tirzepatide as part of standard care, particularly in patients with multiple thrombotic risk factors

These medicines mimic the action of a naturally occurring hormone called GLP-1, which is produced in the intestines in response to food intake

Previous studies have identified advanced age as a major risk factor for the development of both peripheral vestibular disorders and hearing impairment [16, 23]

The 0.4 mg difference reflects the dose found optimal for weight loss in the STEP trials vs the dose found optimal for glycemic control in the SUSTAIN trials

Chronic neuroinflammation is considered an important factor in cognitive and memory impairment in neurodegenerative diseases

With more late-stage clinical trial results forthcoming for this class of drugs, we will soon learn whether the promise of incretin-based therapies is justified