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Among participants on the 12 mg dose, 58.6% achieved at least 25% weight loss, 39.4% achieved at least 30% weight loss, and 23.7% achieved at least 35% weight loss

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The GLP1R weight loss finding from the main study did not replicate in the UK Biobank, though the authors note that the UK Biobank group was too small to reliably detect the effect

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