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However, the second option is free of these issues

A large RCT looking at this, Guide-HF, trial is still enrolling

However, doctors and scientists also noticed the drugs effect on appetite suppression, which has proven highly effective in sustained weight loss

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12 In 2007, Rissmiller and Campo first published a case of seizures induced by bupropion ER (extended release) even though the patient was already receiving two anticonvulsants, including clonazepam, a medication efficacious in preventing bupropion-induced seizures