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[9] [1] Administered as a once-weekly subcutaneous injection, tirzepatide works through dual incretin receptor activation to enhance insulin secretion in a glucose-dependent manner, suppress glucagon release, slow gastric emptying, and reduce appetite

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[1] [3] Symptoms include right upper quadrant or epigastric pain, particularly after fatty meals, along with nausea and vomiting

Remove the needle from your skin

Alexandra Sowa, M.D., a New York City-based physician double-board certified in internal medicine and obesity medicine, and the author of The Ozempic Revolution

Understanding what to expect after your first dose and during each escalation helps set realistic expectations