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GLP-1 and GIP receptor activation can buffer glucagons hyperglycemic potential through glucose-dependent insulin secretion, appetite suppression, delayed gastric emptying, and improved nutrient handling

While they might seem convenient, there is no strong evidence that they work in the same way or deliver the same results as prescription weight loss treatments, such as Wegovy

One detail worth understanding is that phentermine tolerance develops unevenly across patients

In my clinical practice, Ive noticed a trend: Patients on GLP-1 agonists often present with incomplete prep, which can compromise the visibility of the colonic mucosa and increase the risk of missed pathology