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This example underscores a broader point: not all underexplored peptides need to become drugs to influence drug discovery

Human GLP-1 is synthesised from the proglucagon gene and is secreted from the enteroendocrine L cells (1)

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doi: 10.1093/eurheartj/ehz486, PMID: [DOI] [PubMed] [Google Scholar] 24

When you stop the medication, appetite tends to return, and without the pharmacological appetite suppression, a significant portion of lost weight typically comes back unless behavioral habits are strongly maintained

Stromal cell-derived factor-1/Exendin-4 cotherapy facilitates the proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells in vitro and promotes periodontal bone regeneration in vivo