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Description
receptor , pathway therapeutic modulation T2DM .Fine-tuning of GLP-1R/GIPR/GCGRFigure 2

Compare early results with Wegovy and Mounjaro.

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The beneficial effect of TZT in T2DM and obesity is related to direct activation of GIP and GLP-1 receptors with subsequent improvement of insulin sensitivity and reduction of body weight
Although some amelioration of inflammation has been seen, these drugs did not improve the fibrosis component of NASH
