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GLP-1 medications such as Ozempic and Wegovy have significantly reshaped the weight loss market by improving blood sugar regulation, insulin sensitivity, and appetite control

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Glucagon-like peptide-1 receptor (GLP-1R) is a versatile therapeutic target that regulates glucose homeostasis, cardiovascular function, neuroprotection, and immune responses

However, further research is needed to fully understand how these therapies exert their effect on body weight and in the last section we cover open questions about the potential mechanisms of multiagonist drugs, and the understanding of how gutbrain communication can be leveraged to achieve sustained body weight loss without adverse effects.

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