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GLP-1 receptor agonists have demonstrated efficacy in managing both conditions by improving glycemic control and promoting weight loss, making them increasingly prescribed therapeutic options

The muscle loss with GLP-1 is real and the risks of sarcorpenia are real as we go into the future, so it is important to have guidance in this at Prevention Clinics

[DOI] [PubMed] [Google Scholar] 2.Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

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Currently, two ongoing clinical trials are investigating the role of GLP-1 RAs in IBD management, that would lead to further knowledge: a French study (ID NCT05196958) evaluating the safety and efficacy of GLP-1 RAs in treatment of DM2 in overweight IBD patients (115), and an American study (ID NCT06774079) comparing the efficacy of GLP-1 RAs tirzepatide versus diet in CD patients (116)