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The combination Qsymia (phentermine + topiramate) is a separate FDA-approved medication that pairs a low-dose stimulant with an anti-seizure drug but even Qsymia produces less weight loss than semaglutide alone (10% vs 15%)
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[DOI] [PubMed] [Google Scholar] 222.Anderson S, Vora JP

If you notice cold sensitivity coinciding with other symptoms like fatigue or hair loss, ask your provider to check thyroid function and micronutrient levels
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