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Description
Most people describe the nausea as manageable, similar to mild motion sickness
Conversely, combining GLP-1 receptor agonists with other diabetes medications like metformin or SGLT2 inhibitors may enhance glucose control
No impact on bone fractures : If osteoporosis is a concern, the GLP-1 receptor agonists were shown not to increase fracture rates.[ref] Benefits for CVD : In a huge cardiovascular disease study, GLP-1 RAs were shown to be associated with a lower risk of heart attacks and strokes.[ref] Works best with Exercise: A randomized clinical trial found that GLP-1 RAs work best for weight loss when combined with exercise

Sci Rep (2021) 11:137

Zepbound offers scientific support for individuals facing weight challenges

More options for people with these challenging diseases will be very helpful, particularly if the new oral tablet medicines are priced reasonably, he says
