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Diabetes Obes Metab 25: 975984, 2023

Compared to a saline intraperitoneal injection, GIP release was higher following exposure to LPS in mice, and in an IL-6 and IL-1-dependent fashion, with GIP antagonism blunting the inflammatory response

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These medications, such as liraglutide, semaglutide, and tirzepatide, have shown significant results in lowering HbA1c levels and promoting weight loss, which is particularly beneficial for patients with coexisting diabetes and obesity

The AGA specifically suggests continuation of GLP1-RA use until the day or a week prior to the procedure for daily or weekly GLP1-RAs, respectively [195]

Moreover, disease states appear to influence GLP-1R expression patterns