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This hormone signals the pancreas to release insulin as a way to control blood sugar, prompts feelings of fullness, and reduces your appetite

Cell Metab (2019) 30(5):987996.e6

However longer interruptions may sometimes require slower dose escalation to reduce nausea bloating or stomach discomfort during recovery

This is the reason a higher A1c lowering effect is observed with GLP1 agonists, due to the FPG lowering effect

[2] Additionally, findings from SURPASS-1 and SURPASS-2 highlight the importance of gradual dose increases to improve patient adherence and reduce dropouts

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