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Protocol for those on mid-dose tirzepatide (7.5 to 10mg) You are the most common transition candidate

This study will be conducted in collaboration with the Institut de recherches cliniques de Montral (IRCM) (Rmi Rabasa-Lhoret, MD, PhD) and the University of Bern (Lia Bally, MD, PhD

Kadouh, H

Strategies that may prove effective include: Dietary modifications: Tracking food intake for one to two weeks to identify hidden calories or portion creep Increasing protein intake to 1.01.6 grams per kilogram of body weight to preserve lean muscle mass and enhance satiety (with appropriate adjustments for patients with kidney disease) Reducing ultra-processed foods and increasing whole food consumption Implementing structured meal timing to prevent grazing behavior Ensuring adequate fiber intake (women ~2228g, men ~3038g daily, per USDA Dietary Guidelines) to support satiety and metabolic health Physical activity modification represents another critical intervention point

Eligibility Criteria Eligibility criteria for all target trials included a prior diagnosis of type 2 diabetes, a recent medical encounter for type 2 diabetes diagnosis in the past year ( active type 2 diabetes ), prescriptions of antidiabetic medications (semaglutide, tirzepatide, or other antidiabetic medications) between December 2017 and January 2023, and diagnosis with at least 1 condition among the prescription guidelines for semaglutide and tirzepatide (eg, obesity, hypertension, hypercholesterolemia, heart disease, stroke, kidney disease, or an A 1C level 8.5%)

Lifestyle factors, adherence to dosing, and your bodys unique chemistry all play a role in your weight loss journey Side Effects & Safety Both medications have similar side effects, including: Nausea, vomiting, and diarrhea Decreased appetite Potential blood sugar changes However, some patients report that Tirzepatide has a higher likelihood of gastrointestinal side effects in the early weeks of treatment