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The eGFR slope improved from a median of 2.37 mL/min/1.73 m 2 per year before treatment to +0.49 mL/min/1.73 m 2 per year during treatment, indicating significant renoprotective benefits [183]
ER36 lacks the ligand-binding domain residues aa482-595 but retained aa302-465 of ER66
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