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Compounded formulations may not have the same stability-enhancing excipients that brand-name products contain, making them potentially more sensitive to temperature fluctuations

FDA-approved Wegovy and Ozempic undergo strict manufacturing protocols and require exhaustive reporting of side effects, whereas compounding pharmacies operate under less stringent regulations

Wyeth Lab., Inc

Moreover, the simultaneous use of these drugs could prove more beneficial than sequential combination therapy in patients with T2DM, and if similar results are reported with the use of oral GLP-1RAs, it may be easier to initiate the combination earlier in the disease course