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By month four, the routine feels natural, almost invisible in daily life

Johri N et al

REDUCE THE METABOLIC LOAD Substantial sustained weight loss can reduce fat in the liver and pancreas, improve insulin sensitivity and allow surviving beta cells to recover

Because medications for type 2 diabetes may be taken for many years, if GLP-1based therapy did induce low-grade asymptomatic pancreatitis, there is a real concern that such a therapy might increase the risk for pancreatic cancer

Nearly one in five adults with obesity has used a glucagon-like peptide-1 (GLP-1), highlighting the scale of this challenge