glp-1 and alcohol Receptor Agonists Research to Treat Overeating and Substance Use Disorders IUPHAR review – Glucagon-like peptide-1

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This review examines the biological mechanisms underlying GLP-1 RA therapy in MASLD/MASH, analyzes the mechanistic distinctions between mono-, dual-, and triple agonists, and synthesizes current clinical evidence supporting their utilization in individuals with this condition.