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In a double-blind, randomized, placebo-controlled clinical trial, 5% of adolescents in the semaglutide group and 4% in the placebo group discontinued the treatment, due to mainly gastrointestinal adverse events

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In contrast to its known potentiating effect on insulin secretion with the GLP-1 metabolite and weak agonist GLP-1(9-36)NH 2 46 , BETP paradoxically reduced the exendin-4-induced insulin secretion with prolonged incubations (Fig

Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution

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